Each a leader in the field of psilocybin therapy and medicine, Francoise and Rosalind are on the show to talk with each other about psilocybin for depression, trauma, dying; as well as integration, the role of community in getting the most out of our psychedelic experiences, why the depression comes back after psilocybin therapy, and the challenges of being a woman in psychedelic research.

Greg Kieser is on the show to explore a hypothetical future where society is led by Super Aware Intelligence Machines as a framework to talk about systems thinking, supersystemic thinking, idea ecologies, the two cognitive impediments that prevent humanity from solving the largest problems it faces, and where psychedelics are sewn into the mix.

Cannabis nutrigenomics is the study of how hose variants affect our metabolism of cannabis, essentially, how our genes affect our high.